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Image Search Results
Journal: bioRxiv
Article Title: Screening the Medicines for Malaria Pandemic Response Box chemical library on Caenorhabditis elegans identifies re-profiled candidate anthelmintic drug leads
doi: 10.1101/2022.08.10.503491
Figure Lengend Snippet: EC 50 values are determined from concentration-response curves for the 4 compounds consistently showing activity in the growth/motility assay. Each point shows the mean and standard error (error bars) for each concentration tested. Compounds were tested between 10 to 12 replicates and 12 concentrations ranging from 5.0×10 −5 M to 2.0×10 −8 M (tested on three occasions so n=3). EC 50 curves were fitted using a four-parameter log-logistic function in Graphpad Prism 9.3.
Article Snippet: EC 50 values were estimated by fitting curves using a four-parameter log-logistic function in
Techniques: Concentration Assay, Activity Assay, Motility Assay